Do not take trelegy more than prescribed. trelegy may increase your risk of thrush, pneumonia, and osteoporosis. call your doctor if worsened breathing, chest pain, mouth or tongue swelling ...problems urinating, vision changes, or eye pain occur. think your copd medicine is doing enough? maybe you should think again. ask your doctor about once-daily trelegy and the power of 1 2 3. ♪trelegy 1-2-3 save at trelegy.com trust us. us kids are ready to take things into our own hands. don't think so? hold my pouch. you might or joints.hing for your heart... but do you take something for your brain....