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Researchers elucidate how a single mutation causes episodic ataxia type 6

Worldwide, only a handful of patients are known to suffer from episodic ataxia type 6, a neurological disease that causes transient loss of muscle control. ....

Albert Guskov , Emily Henderson , University Of Groningen The Netherlands , Nature Communications , Science Microscopy , Science Microscopy Industry Focus , Amino Acid , Neurological Disease ,

Candida auris escapes innate immunity through metabolic reprogramming

A team of scientists from Australia and Israel demonstrates that Candida auris, a fungus associated with life-threatening and drug-resistant infections, escapes the host's innate immune response by destroying macrophages through metabolic reprogramming. The fungus is also capable of escaping antimicrobial inflammatory response. ....

Kateryna Kon , Science Microscopy , Science Microscopy Industry Focus , Candida Auris , Ell Death , Immune Response ,

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

A recent Nature Signal Transduction and Targeted Therapy journal study demonstrated the potential antiviral activity of a new Mpro inhibitor (SY110) against SARS-CoV-2 Omicron and its sublineages. ....

Naturesignal Transduction , Targeted Therapyjournal , Middle East , Science Microscopy , Science Microscopy Industry Focus , Coronavirus Disease Covid 19 , Ars Cov 2 , Covid 19 , Ers Cov , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

New model could make the measurement of skin barrier function easier

The skin is the primary physical barrier against harmful substances in the environment. But there is a significant difference in the protective capacity of the skin across individuals. ....

Takao Nakamura , Toshimasa Kusuhara , Emily Henderson , Osamu Uehara , Co Ltd , Okayama University , Advanced Biomedical Engineering , Science Microscopy , Science Microscopy Industry Focus ,