Predicting the crystalline nature of APIs with InsituX
Watch this on-demand webinar to learn how to identify active pharmaceutical ingredients solid phase precisely
Source: selectscience.net
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Predicting the crystalline nature of APIs with a novel in-line X-ray technique: InsituX on SelectScience
09 Jun 2021 During drug manufacturing, active pharmaceutical ingredients (APIs) are exposed to variable environmental conditions and encounter multiple stresses, which may lead to phase transformations. Similarly, during storage, solid-state changes can occur and possibly involve a polymorphic transition, solvate formation or desolvation, or interconversion to an amorphous form (Morris, Griesser et al. 2001). The consequences of these changes can affect the performance of an API, and as a result, the quality, stability, and therapeutic effects of the final product may differ from what was exp...
Source: selectscience.net