Study finds that Omicron variant preferentially uses the endosome pathway through mutation in the spike protein
A recent study assessed the role of the SARS-CoV-2 Omicron spike H655Y mutation on viral entry pathways.
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A recent study assessed the role of the SARS-CoV-2 Omicron spike H655Y mutation on viral entry pathways.
A new study posted to the bioRxiv* preprint server has focussed on assessing four members of the NAK family that are associated with SARS-CoV-2 infection. These kininases could act as a target for the development of effective COVID-19 therapeutics.
Researchers investigated how monoclonal antibodies, S309 and AZD7442, reduced lung infection in mice infected with the SARS-CoV-2 new variant of concern Omicron's BA.1, BA.1.1, and BA.2 sublineages.
Researchers demonstrated that combined inhibition of cell-surface-based and endosomal pathways completely blocked SARS-CoV-2 entry into mammalian cells.
In a new study, researchers investigated whether the SARS-CoV-2 spike protein and its S2 subunit induced the expression of C–X–C motif chemokine 10, a subset of cytokine.