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Scientists uncover a new doorway for SARS-CoV-2 into human cells

Research identifies the human transferrin receptor as an alternative pathway for SARS-CoV-2 infection, offering potential new targets for COVID-19 therapies.

Syria , Syrian , Kateryna-kon , Proceedings-of-the-national-academy-sciences , National-academy , Coronavirus-disease-covid-19 , Ars , Ars-cov-2 , Ce2 , Cute-respiratory-distress-syndrome , Ngiotensin , Ngiotensin-converting-enzyme-2

IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

The role of type-2 interferon (IFNγ) in antiviral immunity.

United-states , America , Princejoy-shutterstock , Nature-communications , Bacillus-calmette-gu , Coronavirus-disease-covid-19 , Ovid-19 , Esearch , Ce2 , Ngiotensin , Ngiotensin-converting-enzyme-2 , Ell

COVID-19 tied to elevated risk of benign prostatic hyperplasia complications

SARS-CoV-2 infection linked to increased benign prostatic hyperplasia (BPH) complications and medication use. Urological manifestations in COVID-19 patients emphasize the importance of awareness among clinicians.

Hong-kong , Hong-kong-hospital-authority , Internal-medicine , Hong-kong-hospital , Coronavirus-disease-covid-19 , Rostate , Ce2 , Ngiotensin , Ngiotensin-converting-enzyme-2 , Enign-prostatic-hyperplasia , Oronavirus

Canine transmission models provide insights into the neurological impacts of COVID-19 on human brains

The histopathologic alteration caused by SARS‑CoV‑2 on mammalian neurological systems.

World-health-organization , Emerging-infectious-diseases , Neurologic-effects , Image-credit , Coronavirus-disease-covid-19 , Ovid-19 , Ce2 , Ngiotensin , Ngiotensin-converting-enzyme-2 , Ssay , Lood

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Researchers from the University of Texas Southwestern have developed an aerosolized, mutated form of ACE2 that effectively neutralizes various SARS-CoV-2 variants in both cell cultures and mice. The study suggests that this modified ACE2 has promising preventive and therapeutic potential against COVID-19, especially with its easy aerosolized administration.

United-states , Susha-cheriyedath , University-of-texas-southwestern , Texas-southwestern , Ace2 , Oronavirus-disease-covid-19 , Ngiotensin , Ngiotensin-converting-enzyme-2 , Ell , Oronavirus , Rug-discovery , Fficacy

New omicron variants can reinfect people who were infected with earlier variants

The omicron variants of the SARS-CoV-2 virus, which have rapidly spread around the world over the past year, latch onto our cells more tightly, invade them more efficiently, and elude many of the antibodies induced by previous infections and vaccines.

Aarau , Aargau , Switzerland , Wuhan , Hubei , China , Bellinzona , Ticino , Swiss , David-veesler , Lily-ramsey , Luca-picolli

Unlocking ACE2: The enzyme that links COVID-19, heart disease, and diabetes

A recent study in the Journal of Biomedical Science examines the critical role of ACE2, an enzyme involved in blood volume and electrolyte balance, in chronic diseases like cardiovascular conditions, diabetes, and COVID-19. The research suggests that ACE2 could serve as both a disease severity biomarker and a therapeutic target.

Kateryna-kon-shutterstock , Biomedical-science , Kateryna-kon , Ace2 , Hronic , Oronavirus-disease-covid-19 , Ngiotensin , Ngiotensin-converting-enzyme-2 , Lood , Hronic-disease , Oronavirus

How does COVID-19 influence your gut microbiota?

Researchers analyzed the fecal microbiota composition in COVID-19 patients in comparison to non-COVID-19 controls.

Wuhan , Hubei , China , Vaud , Switzerland-general- , Switzerland , Helsinki , Eteläuomen-läi , Finland , Swiss , Swiss-human-research

SARS-CoV-2 spike pseudovirion infection in ARPE-19 cells is a dynamin-dependent process that is primarily mediated by LDLR

Researchers reported on lentiviral pseudovirions pseudotyped with SARS-CoV-2.

Photocreomichal-bednarek-shutterstock , International-journal-of-molecular-sciences , International-journal , Molecular-sciences , Low-density-lipoprotein-receptor , Lentiviral-particles-pseudotyped , Image-credit , Sars , Ars-cov-2 , Ce2 , Dipose , Ngiotensin

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

Authors explored the impact of SARS-CoV-2 on thymus (T) cell activation.

United-states , Juangaertner-shutterstock , Cell , Ndothelial-cell , Ars , Ars-cov-2 , Ce2 , Ngiotensin , Ngiotensin-converting-enzyme-2 , Lood , Lood-pressure , Hronic