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Plan, where can we scale back on the more aggressive therapies that can lead to life-altering side erck effects and still see positive outcomes. that s the takeaway, kate. in the research they say there are certain types of patients or certain types of cancers where this type of scaling back is not recommended. absolutely. this is where you really have to personalize your approach and one example, i spoke with an oncologist who treats head and neck cancer patients and she said those patients whose cancer associated with hpv. those cancers are more curable than those not associated for lpv. for an hpv-associated patient, they may try the approach, but not those with cancers not associated with hpv. you have to tease out which patient may benefit and which may not qualify. it s interesting. ....