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Likely those children would be to have children with autism. for fathers the risk went up 1.8 times. for mothers the risk went up 1.7 times. it is already known that one piece of the puzzle of autism is the age of the father, starting at age 30. take ray civo. >> let's figure out if there is a genetic factor. >> reporter: his sons oscar and hugo both have autism with different struggles from reading to social interactions. moms pass on few dna mutations. but dads pass on an average of 25 new mutations at age 20. increasing to 65 mutations at age 40 and so on. the more dna mutations, the greate...

To have children with autism. for fathers the risk went up 1.8 times. for mothers the risk went up 1.7 times. it is already known that one piece of the puzzle of autism is the age of the father, starting at age 30. take ray civo. >> let's figure out if there is a genetic factor. >> reporter: his sons oscar and hugo both have autism with different struggles from reading to social interactions. moms pass on few dna mutations. but dads pass on an average of 25 new mutations at age 20. increasing to 65 mutations at age 40 and so on. the more dna mutations, the greater the risk of autism. what does...

Americans were smokers. if you have seen "mad men," you know that is true. in the past 12 years the number of younger smokers has fallen dramatically. a new study from the journal "nature" is shedding light on the mystery behind autism. it turns out the age of the father, it is a key factor in whether a child develops this disorder. abc's medical editor, dr. richard besser, has all the details. >> reporter: autism, one of medicine's greatest puzzles, has some new math, about older dads. dads like ray siegel. >> let's figure out if there is a genetic factor. >> reporter: his sons oscar and hu...