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Process Characterization & Statistical Modeling — Transforming Data into Knowledge Throughout the Product Lifecycle, Upcoming Webinar Hosted by Xtalks

Toronto, ON (PRWEB) July 12, 2022 It’s no surprise that data plays a pivotal role in the biopharmaceutical industry. Parsing through the large amount of ....

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slice Appoints Amazon ICICI Card Chief Sudeep Behari as Business Head

slice Appoints Amazon ICICI Card Chief Sudeep Behari as Business Head
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Read the latest OpenAI headlines, all in one place, on NewsNow: the one-stop shop for news ....

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Frontiers | A Polygenic Score for Type 2 Diabetes Improves Risk Stratification Beyond Current Clinical Screening Factors in an Ancestrally Diverse Sample

A substantial proportion of the adult US population with type 2 diabetes (T2D) are undiagnosed, calling into question the comprehensiveness of current screening practices, which primarily rely on age, family history, and body mass index (BMI). We hypothesized that a polygenic score (PGS) may serve as a complementary tool to identify high-risk individuals. The T2D PGS maintained predictive utility after adjusting for family history and combining genetics with family history led to even more improved disease risk prediction. We observed that the PGS was meaningfully related to age of onset with implications for screening practices: there was a linear and statistically significant relationship between the PGS and T2D onset (-1.3 years per standard deviation of the PGS). Evaluation of U.S. Preventive Task Force and a simplified version of American Diabetes Association screening guidelines showed that addition of a screening criterion for those above the 90th percentile of the PGS provided ....

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Deals Reminder: 2021 Complete Computer Science

Deals Reminder: 2021 Complete Computer Science
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