Computer-Based Modeling Can Predict Mutation "Hotspots" and Antibody Escapers in SARS-CoV-2 Spike Protein
Date Time Computer-Based Modeling Can Predict Mutation “Hotspots” and Antibody Escapers in SARS-CoV-2 Spike Protein Study Identifies Structural Basis of Spike Protein Mutations with Stronger Binding and Antibody Resistance, Which May Explain Transmissibility of New COVID-19 Variants Computational modeling shows that mutations on SARS-CoV-2’s spike protein that enhance the virus’ ability to bind to the ACE2 receptor occur in two clusters or mutation “hotspots.” Image courtesy of Hin Hark Gan and Kristin Gunsalus, NYU’s Department of Biology SARS-CoV-2 has evolved to acquire mu...
Source: miragenews.com