"Associations of Metabolic Hormones and Pro-inflammatory Cytokines with" by Asmahan Elgellaie
Background: Major depressive disorder (MDD) is the most prevalent mental disorder globally, with a greater morbidity rate among females than males. MDD encompasses both psychological and physical symptoms, and is associated with a higher risk of cardiometabolic disease (CMD), encompassing obesity, insulin resistance, dyslipidaemia, and hypertension. This is attributed to shared pathophysiology, including endocrine dysregulation, inflammation, and stress. However, there is limited understanding of the roles of and complex interactions between biological, psychological and physical contributors ...