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Background:Multiple vaccines against Covid-19 have passed through phase-3 trials; however, concerns have been raised about alleged excessive similarity of efficacy across age groups for the Sputnik V vaccine.Study Question:How likely are the observed efficacies for all age subgroups to fall within the range of by-age efficacies claimed for the AstraZeneca, Janssen, Moderna, Pfizer, and Sputnik V vaccines, assuming that there is no effect of age on efficacy?Study Design:We performed a simulation study using R of 1000 and then 50,000 simulated trials for each vaccine, with random allocation to each arm but fixed enrollment numbers by age group. We used study-wide efficacy and infection rate for all age groups. We recorded the observed vaccine efficacies in each age group and summated how many simulations had all observed efficacies fall within the range of efficacies described in the relevant article.Results:In the 1000-trial simulation for the AstraZeneca vaccine, in 23.8% of simulated ....
If she weren t dead. and as i stressed before, it wasn t my fault. says one researcher, playing hard to get makes it seem as if you are more in demand. you call that having higher made value as other people are too easy to attract may be perceived as more desperate. but is this better than the more direct approach? we go to joe devito. greg, we are on the screech of new york. where the direct approach is not working. i ve artie been slapped five times, persuade twice and only spoke with three different women. so i m starting to think ouch. i didn t even talk to you yet. back to you, greg. greg: excellent. all right, kat. do you buy the study question mike i guess. greg: have you ever played hard to get? i can t. i m like no just tell them how you feel. but i think that is why my husband does love me because when i first met him i wasn t ....
If she weren t dead. and as i stressed before, it wasn t my fault. says one researcher, playing hard to get makes it seem as if you are more in demand. you call that having higher made value as other people are too easy to attract may be perceived as more desperate. but is this better than the more direct approach? we go to joe devito. greg, we are on the screech of new york. where the direct approach is not working. i ve artie been slapped five times, persuade twice and only spoke with three different women. so i m starting to think ouch. i didn t even talk to you yet. back to you, greg. greg: excellent. all right, kat. do you buy the study question mike i guess. greg: have you ever played hard to get? i can t. i m like no just tell them how you feel. but i think that is why my husband does love me because ....
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To the next time that you or someone s house gets. when my favorites was this thing that 90% of people surveyed said it is rude to ask for the wi-fi password within 30 minutes of showing up. what struck you in the study question mike funny you mention the first one that jumped out at me because i think i am like most people you come then, you want to have a little conversation, and maybe along the way you need to pick up a call or check email. maybe you ask. but personally, i d like don t ask me for my wi-fi password. i have another one that i noticed in the survey. which i thought was really interesting. i prefer if you would take off your shoes. so like to sort of encourage people, i leave a little pair of shoes outright by the door you can take yours off in that way it s worded gives you a clue into that. in the last one for me, and you probably have a few too, use the spare bathroom. don t go into my bedroom to use my bathroom. just wait. that s my opinion about that. what about ....