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UCB's zilucoplan shows no relevant effect in immune-mediated necrotizing myopathy (IMNM) | Proteins and Peptides


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· No unexpected safety findings and no relevant safety differences between zilucoplan and placebo were identified
· Phase 3 headline results for generalized myasthenia gravis (gMG) are unchanged expected in Q4 2021
BRUSSELS, Belgium I April 22, 2021 I Based on the initial results of a Phase 2 study investigating
zilucoplan in immune-mediated necrotizing myopathy (IMNM), UCB today announced that UCB has decided to not move forward with its IMNM development program. 
The phase 2 study with
zilucoplan, a peptide inhibitor of complement component 5 (C5), in immune-mediated necrotizing myopathy (IMNM) did not show a meaningful effect of
zilucoplan for people living with IMNM. No unexpected safety findings and no relevant safety differences between ....

Bruxelles Capitale , Seanm Healey , Iris Loew Friedrich , Belgiumi April , Chief Medical Officer , Half Year Results , Generalized Myasthenia Gravis , Therapeutic Protein , Binding Proteins , ப்ரூக்ஸெல்ஸ் தலைநகரம் , கருவிழி குறைந்த பிரீட்ரிச் , தலைமை மருத்துவ அதிகாரி , பாதி ஆண்டு முடிவுகள் ,

Chinese and Mexican Criminal Entities Team Up to Traffick a New Drug Capable of Doing


Chinese and Mexican Criminal Entities Team Up to Traffick a New Drug Capable of Doing
Chinese and Mexican Criminal Entities Team Up to Traffick a New Drug Capable of Doing Great Harm to Americans
Hollie McKay of
CNS News covered the rise of isotonitazene and its deleterious effects stateside.
“In the last twelve months, I have seen a number of overdose cases, where the person isn’t responding at all to the Naloxone, which made us realize this wasn’t fentanyl,” an anti-drug campaigner based in California observed. The activist’s reference to Naloxone is relevant, because this is a nasal spray used on people who suspectedly overdose on fentanyl. It’s often referred to as a miracle medicine by paramedics, literally capable of bringing overdose victims back to life. ....

News Stories , General Discussion , செய்தி கதைகள் , ஜநரல் கலந்துரையாடல் ,

Analysis of Oligonucleotides and their Related Substances  Labmate Online


Apr 14 2021 Read 5 Times
Oligonucleotides are growing in importance in the pharmaceutical and biotechnology industries as therapeutic medicines to address significant medical needs that are so far unmet. Over the past decades, research into synthetic oligonucleotides as therapeutic medicines has grown as they have the potential to be used as highly targeted medicines to treat a range of diseases, particularly genetic disorders.
However, oligonucleotides are a unique class of molecules and their structure and analysis make them one of the most challenging tasks for analytical chemists, and thus require a different approach to existing medicinal products. 
For successful research and development, it is necessary to acquire new skills and knowledge in the field of oligonucleotides analysis. This book, Analysis of Oligonucleotides and their Related Substances, provides various analytical technologies that are in frequent use in modern research and reviews the most up-to- ....

Related Substances ,