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Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy - Vimarsana News

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

Mark Sundrud, PhD: Bile Acid and T Cell Interplay in Cholestatic Diseases - Vimarsana News

Mark Sundrud, PhD: Bile Acid and T Cell Interplay in Cholestatic Diseases

We sat down with Mark Sundrud, PhD, to discuss bile acids and T cells in cholestatic liver disease and the future of research regarding the interplay between intestinal and liver functions.

Galapagos enlists Landmark Bio to manufacture CAR-T therapies - Vimarsana News

Galapagos enlists Landmark Bio to manufacture CAR-T therapies

The Belgian biotech company Galapagos will work with Landmark Bio to deliver CAR-T cell therapies to patients more quickly than with traditional manufacturing methods.

Atara licenses T cell therapy to Pierre Fabre for up to $640 million - Vimarsana News

Atara licenses T cell therapy to Pierre Fabre for up to $640 million

As it extends its cash runway, the cell therapy developer Atara Biotherapeutics has expanded a partnership with Pierre Fabre Laboratories to commercialize the off-the-shelf T-cell therapy tabelecleucel (tab-cel) for a rare form of blood cancer.

Novel replacement strategy holds promise for the treatment of various genetic disorders - Vimarsana News

Novel replacement strategy holds promise for the treatment of various genetic disorders

Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer cell function and counts.