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While most CKD cases originate from lifestyle-related factors or diseases such as diabetes and hypertension, the underlying causes of CKD remain unknown for about one in every ten people with end-stage renal failure.
Chronic kidney disease (CKD) is extremely prevalent among adults, affecting over 800 million individuals worldwide.
Study offers clues to clinical diagnosis of nephronophthisis in adults Nephronophthisis (NPH) is a kidney disease affecting mainly children. Now, for the first time, researchers at Tokyo Medical and Dental University (TMDU) have studied a number of adults with NPH and highlighted clinical, genetic and pathological characteristics that could help in confirming this challenging diagnosis. NPH is inherited in an autosomal recessive pattern and, though rare, is the commonest genetic cause of kidney failure in children. The name is derived from 'nephron', the functional filtration units of the kid...
E-Mail IMAGE: Genetic background and clinical features of adult patients suspected with nephronophthisis on renal biopsy view more Credit: Department of Nephrology,TMDU Researchers at Tokyo Medical and Dental University (TMDU) in a pioneering study identify clinical, genetic and histopathological characteristics that may help confirm the diagnosis when nephronophthisis occurs in adults Tokyo, Japan - Nephronophthisis (NPH) is a kidney disease affecting mainly children. Now, for the first time, researchers at Tokyo Medical and Dental University (TMDU) have studied a number of adult...