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Pancreatic ductal adenocarcinoma (PDAC), that arises from pancreatic epithelial cells, is the most common form of pancreatic cancer, with a very high mortality rate.
<p style="text-align:justify"><strong>The treatment of pancreatic cancer, an aggressive form of cancer associated with high mortality rates, is challenging owing to limited options and anticancer screening models. High mortality has been attributed to the unique tumor microenvironment (TME). Researchers from Japan have created a pancreatic ductal adenocarcinoma (PDAC) organoid model using human-induced pluripotent stem cell (hiPSC) technology, simulating desirable TME properties. Their research findings have far-reaching consequences in the field of cancer biology.</st...