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Model demonstrates how RNA splicing defects contribute to Alzheimer s disease

Scientists at St. Jude Children’s Research Hospital created a model to study the role of RNA splicing defects in Alzheimer’s disease, revealing degeneration

South koreaElizabeth stewartXusheng wangTudor moldoveanuDonnie eddinsJi hoon choYingxue fuMichael dyerZhen wangMingming niuYawei huiGeidy serranoJoseph mertzAriana mancieriTaosheng chenChuan sun

Model demonstrates how RNA splicing defects contribute to Alzheimer s

Model demonstrates how RNA splicing defects contribute to Alzheimer s
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South koreaElizabeth stewartXusheng wangTudor moldoveanuDonnie eddinsJi hoon choYingxue fuMichael dyerZhen wangMingming niuYawei huiGeidy serranoJoseph mertzAriana mancieriTaosheng chenChuan sun

Understanding how autoactivation triggers cell death

Geetika Singh, Ph.D., St. Jude departments of Structural Biology and Chemical Biology and Therapeutics, first author of the paper published in Nature

Cristina guibaoDan mcnamaraTudor moldoveanuGeetika singhSivaraja vaithiyalingamJayaraman seetharamanAnup aggarwalM brett waddellNature communicationsNational cancer instituteJude children research hospitalNational instituteJude comprehensive cancer centerStructural biologyChemical biologyJude children