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New study uncovers how altered gene expressio

<p><strong>The loss-of-function mutation of <em>KMT2C</em>, a gene involved in histone modification, leads to the development of autism and other neurodevelopmental deficits. However, the precise mechanism of the disease progression is still unknown. Now, researchers from Japan have developed an animal model and elucidated the mechanism by which mutation in genes involved in chromatin modification causes autism. They have also discovered a drug that can be used in the treatment of autism.</strong></p>
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Japan General , Shigehiro Kuraku , Tadafumi Kato , Kurara Honda , Takumi Nakamura , Atsushi Takata , Junko Ueda , Takashi Tsuboi , Mizuho Ishiwata , Toru Takumi , Tomonori Hara , Shigeyoshi Itohara , Toru Yoshihara , Takaoki Kasahara , Chiharu Tanegashima , Yuki Kobayashi , Masahide Asano , Sumitomo Dainippon Pharma , Moe Nakanishi , Mitsutaka Kadota , Kazuo Nakajima , Teikyo University School Of Medicine , Research Institute For Diseases Of Old Age , Carl Von Ossietzky University Of Oldenburg , Department Of Genetics , Laboratory For Behavioral Genetics ,