Jan 11, 2021 Consensus guideline recommendations have little effect on treatment decisions Most older adults with primary hyperparathyroidism (PHPT) did not receive definitive treatment with parathyroidectomy, instead receiving non-operative management, researchers reported. According to a population-based cohort study, older age, frailty, and multimorbidity had inverse associations with parathyroidectomy — and guideline recommendations had minimal impact on treatment decisions, “especially among frail patients with a high comorbidity burden,” wrote Carolyn D. Seib, MD, MAS, Department ...