Newly Identified Embryonic Brain Circuit Provides Insights into Autism
Researchers say their methods will aid study into the effects of genes associated with neurodevelopmental disorders, in particular autism.
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Researchers say their methods will aid study into the effects of genes associated with neurodevelopmental disorders, in particular autism.
Using a new approach for studying live embryonic mouse brains at single-cell resolution, researchers have identified an active multi-layer circuit that forms in the cortex during an unexpectedly early stage of development. Perturbing the circuit genetically led to changes similar to those seen in the brains of people with autism. The findings are reported today in Cell by a team based at the Institute of Molecular and Clinical Ophthalmology Basel.
EMBARGOED UNTIL 17-APR-2023 11:00 ET The findings may provide new insights into...