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Newly Identified Embryonic Brain Circuit Provides Insights into Autism

Researchers say their methods will aid study into the effects of genes associated with neurodevelopmental disorders, in particular autism. ....

Martin Munz , Arjun Bharioke , Botond Roska , Central Visual Circuits Group , Institute Of Molecular , Clinical Ophthalmology Basel , Visual Circuits Group , Central Visual Circuits ,

IOB researchers identify an active multi-layer embryonic brain circuit

Using a new approach for studying live embryonic mouse brains at single-cell resolution, researchers have identified an active multi-layer circuit that forms in the cortex during an unexpectedly early stage of development. Perturbing the circuit genetically led to changes similar to those seen in the brains of people with autism. The findings are reported today in Cell by a team based at the Institute of Molecular and Clinical Ophthalmology Basel. ....

Arjun Bharioke , Botond Roska , Martin Munz , Danielle Ellis , Central Visual Circuits Group , Institute Of Molecular , Clinical Ophthalmology , Visual Circuits Group , Central Visual Circuits ,

Researchers Discover a New Embryonic Brain Circuit

EMBARGOED UNTIL 17-APR-2023 11:00 ET The findings may provide new insights into. ....

Georg Kosche , Alexandra Graff Meyer , Simone Picelli , Talia Ulmer , Brigitte Gross Scherf , Arjun Bharioke , Camerons Cowan , Dinko Pavlinic , Jacek Krol , Stephanie Haeuselmann , Nicole Ledergeber , Botond Roska , Alexandra Brignall , Tiagom Rodrigues , Martin Munz , University Of Basel , University Hospital Basel , Central Visual Circuits Group , Institute Of Molecular , Clinical Ophthalmology , Visual Circuits Group , Clinical Ophthalmology Basel , Institute Of Molecular And Clinical Ophthalmology Basel Iob , Neural Circuit ,