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Researchers present a novel approach to single-cell RNA sequencing (scRNA-seq) called “Live-seq”, which enables the extraction of mRNA from single cells without killing the cell. The method is published in <i>Nature</i>.
RNA sequencing allows scientists to study the expression of genes in a cell. Since messenger RNA (mRNA) is generated from a DNA gene, that information can be used to identify the original gene sequence and thus measure the activity of thousands of genes (i.e. the transcriptome) in these cells.