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Last year, 3,316 semaglutide overdoses were reported by 55 poison control centers in the U.S. Compounded versions, which can contain semaglutide salts, are likely behind most of the overdoses.
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Ozempic, Wegovy, and Saxenda are under investigation by the European Medicines Agency for possibly causing consumers to self-harm or experience suicidal thoughts. Clinical trials of the drug did not see this to be a large risk factor, but experts note a changing population of those taking the drugs may have shifted risk levels.
When insurance won’t pay for Ozempic, Wegovy, or Mounjaro, people are turning to cheaper, compounded semaglutide and tirzepatide — despite the risks.
When a person with diabetes, high blood pressure, or osteoarthritis goes to their primary care clinic, they expect treatment that's grounded in modern medical evidence.