Twisters spins original story, unconnected to original, says scribe
While Universal Pictures did toy with doing a straight-up sequel to Twister (1996), with Helen Hunt reprising her role as, the studio ultimately opted to go the way of a reboot - one without any link to the original, it seems. "It was something that [original Twisters director] Joe Kosinski and I came up with," writer Mark L. Smith said of next year's Twisters in an interview [...]
Source: moviehole.net