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Teclistamab/Talquetamab Combo Shows Early Safety, Efficacy in R/R Multiple Myeloma

Teclistamab-cqyv in combination with talquetamab showcased early signs of activity with acceptable safety in patients with relapsed/refractory multiple myeloma, according to final results from the phase 1b RedirecTT-1 study. ....

Tocilizumab Actemra , Yaelc Cohen , Andrzejj Jakubowiak , Aviv Sourasky Ichilov Medical Center , International Stating System , Tel Aviv University , University Of Chicago , Department Of Hematology , Sackler School Of Medicine , Tel Aviv Sourasky , Medical Center , Sackler School , Tel Aviv , Multiple Myeloma , Redirectt 1 Study ,

Uncovering the Anti-Myeloma Resistance Files


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Multiple myeloma (a type of blood cancer) patients live much longer today than in the past, thanks to new targeted anti-myeloma drugs, but ultimately most develop resistance to the medications, and in some the disease is resistant to therapy from the start. Weizmann Institute of Science researchers, in collaboration with physicians from 
Tel Aviv Sourasky Medical Center (TASMC), have made use of extremely sensitive genomic technology to reveal genetic pathways that characterize some of the more resistant cases of multiple myeloma. 
Nature Medicine, may lead to a more informed, personalized treatment for these patients, and it paves the way to using this new technology for discovering additional disease targets in other cancers. ....

Mouna Ballan , Tamar Tadmor , Yaelc Cohen , Gadi Moshe , Oren Pasvolsky , Chezi Ganzel , Meirav Laiba , Chamutal Bornstein , Baoguo Li , Eyal David , Jacqui Scheinberg , Ido Amit , Assaf Weiner , Osnat Jarchowcky Dolberg , Efrat Luttwak , Noa Lavi , Mor Zada , Irit Avivi , Olga Shvetz , Chamutal Gur , Evgeni Chubar , Iuliana Vaxman , Ofer Shpilberg , Anatoly Nemets , Anita James Rosen Foundation , Moross Integrated Cancer Center ,