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Cleveland Orchestra covers Baroque, Christmas bases with spirited fourth 'In Focus' episode


Cleveland Orchestra covers Baroque, Christmas bases with spirited fourth ‘In Focus’ episode
Zachary Lewis, cleveland.com
CLEVELAND, Ohio – Filtered lights. Television cameras. Digital interaction. Visually, the Cleveland Orchestra’s fourth “In Focus” episode bears little resemblance to real life in the Baroque era.
Boy, though, does it sound authentic. This may be Severance Hall in late 2020, but under the spry, insightful watch of Nicholas McGegan, the orchestra in this program sounds like the resident ensemble of some European palace in the 1700s.
Some of the credit must go to the medium, the Adella streaming app, which again delivers a rich, engaging, and musically satisfying experience. The cameras are as intelligent as can be, training on all the right subjects, and so true is the audio fidelity, one might as well be seated next to McGegan, turning pages at the harpsichord.

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Exploring how prostate cancer cells resist treatment


Exploring how prostate cancer cells resist treatment
December 10, 2020
Research could provide a pathway for prostate cancer therapeutics
Research by a University of Georgia scientist sheds light on how two genes factor into prostate cancer cells becoming resistant to treatment, providing a potential new target for therapeutics.
The two genes, ACSL3 and ACSL4, are from the same family and help cancer cells grow, according to Houjian Cai, associate professor in the College of Pharmacy. He and a team of researchers found that the genes function in an interconnected way, similar to the concept of yin and yang.
Prostate cancer is the second leading cause of cancer deaths among men in the United States, according to the Centers for Disease Control. Castration treatment, the primary therapy used to fight prostate cancer, suppresses the male hormone that helps the cancer grow. With this therapy, expression of the ACSL3 gene typically becomes low, according to Cai.

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