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Stopping Zika: Engineering an Alternative to 'Suicide Mosquitoes'

A new study from the University of Missouri and Colorado State University outlines the application of CRISPR gene-editing technology to produce mosquitoes that are unable to replicate Zika virus, rendering them unable to infect humans.
The Zika virus epidemic is a pressing public health emergency. In Brazil for example, there has been a 10-fold increase in newborns with microcephaly since October 2015, compared with previous years. Researchers have wrestled with various strategies for controlling the spread of Zika virus, which is transmitted to humans from female mosquito bites.
One approach, which was approved by the Environmental Protection Agency in May, will release more than 750 million genetically modified mosquitos into the Florida Keys in 2021 and 2022. These “suicide mosquitos” are genetically-altered to produce offspring that die before emerging into adults and therefore cannot bite humans and spread disease. ....

Alexander Franz , University Of Missouri , Colorado State University , Mu College Of Veterinary Medicine , Environmental Protection Agency , Florida Keys , Veterinary Medicine , Induces Zika Virus Resistance , Transgenic Aedes , அலெக்சாண்டர் ஃப்ரான்ஸ் , பல்கலைக்கழகம் ஆஃப் மிச Ou ரி , கொலராடோ நிலை பல்கலைக்கழகம் , மு கல்லூரி ஆஃப் கால்நடை மருந்து , புளோரிடா விசைகள் , கால்நடை மருந்து ,

Suicide mosquitos may prevent the spread of Zika virus

Suicide mosquitos may prevent the spread of Zika virus
In 2016, the World Health Organization called the Zika virus epidemic a public health emergency of international concern due to the virus causing birth defects for pregnant women in addition to neurological problems. Since then, researchers have wrestled with different strategies for controlling the spread of Zika virus, which gets transmitted to humans from female mosquito bites.
One approach, which was approved by the Environmental Protection Agency in May, will release more than 750 million genetically modified mosquitos into the Florida Keys in 2021 and 2022. These suicide mosquitos are genetically-altered to produce offspring that die before emerging into adults and therefore cannot bite humans and spread disease. ....

Alexander Franz , Emily Henderson , University Of Missouri , Colorado State University , Mu College Of Veterinary Medicine , World Health Organization , Environmental Protection Agency , Florida Keys , Veterinary Medicine , Associate Professor , Zika Virus , Birth Defects , Public Health , அலெக்சாண்டர் ஃப்ரான்ஸ் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் மிச Ou ரி , கொலராடோ நிலை பல்கலைக்கழகம் , மு கல்லூரி ஆஃப் கால்நடை மருந்து , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , புளோரிடா விசைகள் , கால்நடை மருந்து , இணை ப்ரொஃபெஸர் , ஜிக வைரஸ் , பிறப்பு குறைபாடுகள் , பொது ஆரோக்கியம் ,

Modified mosquitoes could stop Zika virus spread

Using CRISPR gene-editing technology, researchers have produced mosquitoes unable to replicate Zika virus and therefore also unable to infect a human through biting.
In 2016, the World Health Organization called the Zika virus epidemic a “public health emergency of international concern” due to the virus causing birth defects for pregnant women in addition to neurological problems.
Since then, researchers have wrestled with different strategies for controlling the spread of Zika virus, which gets transmitted to humans from female mosquito bites.
One approach, which the Environmental Protection Agency approved in May, will release more than 750 million genetically modified mosquitoes into the Florida Keys in 2021 and 2022. These “suicide mosquitoes” are genetically-altered to produce offspring that die before emerging into adults and therefore cannot bite humans and spread disease. ....

Alexander Franz , Environmental Protection Agency , University Of Missouri College Veterinary Medicine , National Institutes Of Health , World Health Organization , Florida Keys , Missouri College , National Institutes , அலெக்சாண்டர் ஃப்ரான்ஸ் , பல்கலைக்கழகம் ஆஃப் மிச Ou ரி கல்லூரி கால்நடை மருந்து , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , புளோரிடா விசைகள் , மிச Ou ரி கல்லூரி , தேசிய நிறுவனங்கள் ,

Genetically-modified mosquitoes key to stopping Zika virus spread

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IMAGE: Dr. Alexander Franz is an associate professor in the MU College of Veterinary Medicine.
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Credit: MU College of Veterinary Medicine
COLUMBIA, Mo. - In 2016, the World Health Organization called the Zika virus epidemic a public health emergency of international concern due to the virus causing birth defects for pregnant women in addition to neurological problems. Since then, researchers have wrestled with different strategies for controlling the spread of Zika virus, which gets transmitted to humans from female mosquito bites.
One approach, which was approved by the Environmental Protection Agency in May, will release more than 750 million genetically modified mosquitos into the Florida Keys in 2021 and 2022. These suicide mosquitos are genetically-altered to produce offspring that die before emerging into adults and therefore cannot bite humans and spread disease. ....

Alexander Franz , Irma Sanchez Vargas , Adelinee Williams , Kene Olson , Jingyi Lin , Williamr Reid , University Of Missouri , Colorado State University , Mu College Of Veterinary Medicine , National Institutes Of Health , World Health Organization , Environmental Protection Agency , Florida Keys , Veterinary Medicine , Antiviral Small Interfering , Induces Zika Virus Resistance , Transgenic Aedes , National Institutes , அலெக்சாண்டர் ஃப்ரான்ஸ் , இர்மா சான்செஸ் வர்காஸ் , பல்கலைக்கழகம் ஆஃப் மிச Ou ரி , கொலராடோ நிலை பல்கலைக்கழகம் , மு கல்லூரி ஆஃப் கால்நடை மருந்து , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , புளோரிடா விசைகள் ,