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Researchers identify an unexpected effect for already characterized active substances


Researchers identify an unexpected effect for already characterized active substances
Every innovative drug starts with the search for an active substance targeting key players in disease-related processes. However, there is no perfect drug that affects the one target in the body: no effect without side effects, as also described in most medicine information leaflets. A group of chemists and biologists led by Prof. Herbert Waldmann and Dr. Slava Ziegler at the Max Planck Institute of Molecular Physiology in Dortmund have now combined different strategies to find bioactive molecules and identified an unexpected effect for a group of already characterized active substances: they all modulate cholesterol metabolism, a home-made problem, as it seems. ....

Slava Ziegler , Tabea Schneidewind , Herbert Waldmann , Alexander Flemming , Emily Henderson , Max Planck Institute Of Molecular Physiology , Max Planck Institute , Molecular Physiology , Cell Painting Assay , ஹெர்பர்ட் வால்ட்மேன் , அலெக்சாண்டர் பிளெமிங் , எமிலி ஹென்டர்சன் , மூலக்கூறு உடலியல் ,

Characterized drugs show unexpected effects

Characterized drugs show unexpected effects
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Slava Ziegler , Tabea Schneidewind , Herbert Waldmann , Alexander Flemming , Cell Painting Assay , ஹெர்பர்ட் வால்ட்மேன் , அலெக்சாண்டர் பிளெமிங் ,