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MOMI-Vax study evaluates COVID-19 vaccination during pregnancy and postpartum

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Emory University is participating in a study evaluating immune responses to COVID-19 vaccines, when the vaccines are administered during pregnancy or within two months after delivery.
The study, called SARS-CoV-2 Vaccines in Pregnancy and Postpartum or MOMI-Vax, is sponsored and funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. MOMI-Vax is being conducted by the NIAID-funded Infectious Diseases Clinical Research Consortium (IDCRC).
MOMI-Vax is open to people who have received any of the FDA-authorized COVID-19 vaccines. The early COVID-19 vaccine clinical trials generally excluded pregnant women, so there is limited data on immune responses for this special population. However, after the FDA authorized the vaccines, regulators gave people who were pregnant or soon to be pregnant the option of choosing to get the vaccines. Tens of thousands of pregnant and breastfeeding people across the co ....

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Transfer of COVID-19 antibodies from pregnant women to newborns lower than expected

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Women who contract COVID-19 during pregnancy are able to make strong neutralizing antibodies but may end up passing fewer of these protective antibodies to their infants than desired, a new study at Emory University shows.
Researchers from Emory’s Obstetrics and Gynecology department and Emory Vaccine Center looked at a sample of pregnant women who were infected with the new coronavirus at some point during their pregnancy. They found that 94 percent of the maternal blood samples contained neutralizing antibodies while only 25 percent of cord blood contained the same antibodies.
The researchers also investigated whether the timing of infection in pregnancy made a difference in the levels of antibodies present, or whether the presence of COVID-19 symptoms at the time of diagnosis affected antibody levels. They found that neither factor seemed to impact neutralizing antibody levels, which suggests that women do not have to be severely ill to be protected, and ....

Vijayakumar Velu , Naima Joseph , Gynecology Department , Emory Vaccine Center , Emory University , Society For Maternal , Grady Memorial Hospital , Emory University Midtown , Opportunistic Infection , Maternal Fetal Medicine , விஜயகுமார் வேலு , நைமா ஜோசப் , பெண்ணோயியல் துறை , உணர்ச்சி தடுப்பூசி மையம் , உணர்ச்சி பல்கலைக்கழகம் , சமூகம் க்கு தாய்வழி , கிரேடி நினைவகம் மருத்துவமனை , உணர்ச்சி பல்கலைக்கழகம் மிட் டவுன் , தாய்வழி கரு மருந்து ,