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Starbucks, Flush With Customers, Is Running Low on Ingredients

At locations across the country, there have been complaints about shortages of key ingredients for popular drinks, breakfast foods and even cups, lids and straws. ....

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Manufacturing: Once A Great Equalizer, Now A Competitive Advantage

With microfactories, the investment in time and training required to bring an innovation to market decreases dramatically. They bring us a giant step closer to enabling anyone with an idea to make that idea a physical reality, and to bring it to market at a reasonable price. ....

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Transformative Mega Trends Enabling Lights Out Manufacturing

Transformative Mega Trends Enabling Lights Out Manufacturing
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DRDO To Transfer Technology Of Anti-COVID Drug '2-DG' To India Pharma Firms, Invites EoI


DRDO To Transfer Technology Of Anti-COVID Drug 2-DG To India Pharma Firms, Invites EoI
by Swarajya Staff - Jun 9, 2021 07:25 AM
DRDO Logo (Pic Via Wikipedia)
The Defence Research and Development Organisation (DRDO) has sought Expression of Interest (EoI) for transfer of technology for bulk manufacturing of the 2-Deoxy-D-Glucose (2-DG), a drug developed by the DRDO for treatment of Covid-19 patients.
The drug has been developed by the Institute of Nuclear Medicine and Allied Sciences (INMAS), a lab of the DRDO, in collaboration with Dr Reddy s Laboratories (DRL), Hyderabad.
2-DG is a glucose analogue, which has the 2-hydroxyl group replaced by hydrogen. The molecule is transported in cells by the glucose transporters on the cell membrane but it cannot undergo further glycolysis and act as inhibitor of glycolysis. Therefore, cells with higher glucose uptake, for example tumor cells, virally infected cells, inflammatory cells have also a higher uptake of 2-DG. ....

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