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Painting picture of breast cancer spread


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Painting picture of breast cancer spread
A new study has shed coloured light on how an aggressive breast cancer spreads to vital organs, paving the way for more targeted drug treatments for patients.
Published today in Science Advances, the study used fluorescent proteins derived from jellyfish and sea anemones to ‘paint a picture’ of how breast cancer cells adapt and colonise other tissues, in particular the liver and lungs.
Postdoctoral Research Fellow at the Olivia Newton-John Cancer Research Institute and La Trobe University’s School of Cancer Medicine, Dr Jean Berthelet, said understanding how cancer cells travel to, and survive in, distant organs, is critical to the development of effective cancer treatments. ....

Jean Berthelet , Susang Komen , Frederic Hollande , Kelly Rogers , Delphine Merino , Verena Wimmer , Eliza Hall Institute , Laboratory Head , Australian National Breast Cancer Foundation , Cancer Council Victoria , Postdoctoral Research , University Of Melbourne , Trobe University School Of Cancer Medicine , Trobe Institute Of Molecular Science , Trobe School Of Cancer Medicine , Olivia Newton John Cancer Research Institute , Science Advances , Research Fellow , Cancer Medicine , Professor Frederic Hollande , Triple Negative Breast Cancer , Cancer Australia , Olivia Newton John Cancer Research , சுசாங் கோமேன் , கெல்லி ரோஜர்ஸ் , எலிசா மண்டபம் நிறுவனம் ,

Researchers discover way to improve immune response

New cellular atlas maps out healthy and cancerous breast tissue


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New cellular atlas maps out healthy and cancerous breast tissue
WEHI researchers have documented the diversity of cells in the human breast, explaining the relationship between healthy breast cells and breast cancer cells.
The diversity of cells in the human breast has been
documented in a new ‘RNA atlas’.
The research, which relied on expertise spanning from breast cancer biology through to bioinformatics, measured gene expression in single cells taken from healthy women and cancerous breast tissue, including tissue carrying a faulty BRCA1 gene. This enabled the researchers to create an ‘RNA atlas’ that details the different cells found in these tissues. ....

Tony Papenfuss , Jane Visvader , Geoff Lindeman , Gordon Smyth , Yunshun Chen , Rachel Joyce , Bhupinder Pal , Stephen Wilcox , Jocelyn Penington , Vanessa Bryant , Nina Tubau Ribera , Bianca Capaldo , National Health , Qualtrough Cancer Research Fund , Michael Heine Family Foundation , Ian Potter Foundation , Australian Cancer Research Foundation , National Breast Cancer Foundation , Research Council , Olivia Newton John Cancer Research Institute , Professor Jane Visvader , Professor Gordon Smyth , Professor Geoff , Professor Visvader , Professor Smyth , Victorian Cancer Biobank ,