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Study may lead to new treatment for incurable brain cancer in children

Study may lead to new treatment for incurable brain cancer in children
Research by Australian scientists could pave the way to a new treatment for a currently incurable brain cancer in children called Diffuse Intrinsic Pontine Glioma, or DIPG. Affecting about 20 children in Australia each year, DIPG is a devastating disease with an average survival time of just nine months after diagnosis.
The research, led by scientists at Children s Cancer Institute and published this week in the international journal,
Cell Reports, offers an exciting new therapeutic approach for the treatment of DIPG by using a new anti-cancer drug.
The new drug, CBL0137, is an anti-cancer compound developed from the antimalarial drug quinacrine. The researchers found that CBL0137 directly reverses the effects of the key genetic drivers in DIPG, and has a profound effect against DIPG tumor models. ....

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Potential treatment advance for aggressive childhood cancer revealed

Potential treatment advance for aggressive childhood cancer revealed
unsw.edu.au - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from unsw.edu.au Daily Mail and Mail on Sunday newspapers.

New South Wales , David Ziegler , Kids Cancer Centre , Group Leader At Children Cancer Institute , Children Cancer Institute , Diffuse Intrinsic Pontine Glioma , Cancer Institute , Cell Reports , Associate Professor David Ziegler , Group Leader , Sydney Children , Professor Ziegler , Associate Professor , Prof Ziegler , புதியது தெற்கு வேல்ஸ் , டேவிட் ஸீக்லர் , கீட்ஸ் புற்றுநோய் மையம் , குழு தலைவர் இல் குழந்தைகள் புற்றுநோய் நிறுவனம் , குழந்தைகள் புற்றுநோய் நிறுவனம் , புற்றுநோய் நிறுவனம் , செல் அறிக்கைகள் , இணை ப்ரொஃபெஸர் டேவிட் ஸீக்லர் , குழு தலைவர் , சிட்னி குழந்தைகள் , ப்ரொஃபெஸர் ஸீக்லர் , இணை ப்ரொஃபெஸர் ,

Australian researchers find new way to target deadly childhood cancer

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Research by Australian scientists could pave the way to a new treatment for a currently incurable brain cancer in children called Diffuse Intrinsic Pontine Glioma, or DIPG. Affecting about 20 children in Australia each year, DIPG is a devastating disease with an average survival time of just nine months after diagnosis.
The research, led by scientists at Children s Cancer Institute and published this week in the international journal,
Cell Reports, offers an exciting new therapeutic approach for the treatment of DIPG by using a new anti-cancer drug.
The new drug, CBL0137, is an anti-cancer compound developed from the antimalarial drug quinacrine. The researchers found that CBL0137 directly reverses the effects of the key genetic drivers in DIPG, and has a profound effect against DIPG tumour models. They also foundCBL0137 is even more effective when combined with a second drug, panobinostat, a new type of drug known as a histone deacetylase (HDAC) inhib ....

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