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Discovery by South African scientists gives new hope fo...

South African scientists, as part of an international research collaboration, identified chemical compounds with anti-tubercular and anti-cancer properties that can help in the fight against malaria. The compounds could halt a malaria parasite in its tracks during different stages of the parasite’s life cycle.
This discovery is significant given growing concerns about malaria drug resistance and the need for new malaria drugs.
The collaborative efforts of chemists, biologists and pharmacologists from South Africa led to this discovery, signalling new hope for eradicating malaria.
“It’s an outcome of a massive amount of teamwork and collaboration in South Africa. To be able to work together with other South African scientists of this calibre and on this level was extraordinary,” says Professor Lyn-Marie Birkholtz, head of the University of Pretoria’s Malaria Parasite Molecular Laboratory. ....

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Teamwork and infrastructure behind local malaria discovery, researchers say

Local scientists, as part of an international research collaboration, identified chemical compounds with antitubercular and anti-cancer properties that can now help in the fight against malaria.
The compounds could halt a malaria parasite in its tracks during different stages of the parasite’s life cycle. This discovery is significant given growing concerns about malaria drug resistance and the need for new malaria drugs.
The collaborative efforts of chemists, biologists and pharmacologists from South Africa have led to this discovery, signalling new hope for eradicating malaria.
“It’s an outcome of a massive amount of teamwork and collaboration in South Africa. To be able to work together with other South African scientists of this calibre and on this level was extraordinary,” says Professor Lyn-Marie Birkholtz, head of the University of Pretoria’s Malaria Parasite Molecular Laboratory. ....

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Wits University scientists artificially infect mosquitoes with human malaria to advance treatment

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IMAGE: Scientists at the Wits Research Institute for Malaria, with local and global partners, have artificially infected mosquitoes with human malaria and identified a new chemical compound to treat malaria.
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Credit: Wits University
A vector refers to an organism that carries and transmits an infectious disease, as mosquitoes do malaria.
Lead compounds are chemical compounds that show promise as treatment for a disease and may lead to the development of a new drug.
Antiplasmodial lead compounds are those that counter parasites of the genus Plasmodium, which is the parasite that infects mosquitoes and causes malaria in people. ....

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2021-01 - Wits scientists artificially infect mosquitoes with human malaria to advance treatment

2021-01 - Wits scientists artificially infect mosquitoes with human malaria to advance treatment
wits.ac.za - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from wits.ac.za Daily Mail and Mail on Sunday newspapers.

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SA researchers may have found a way to cure malaria

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Curing malaria means also having to stop the transmission cycle, which the new potent chemical compounds will be able to do.
Residents in Burkina Faso have struggled to contain malaria. Picture for illustration: iStock
The groundbreaking discovery was published in the
Nature Communications journal on Monday.
It involved identifying compounds able to kill several stages of the deadly human malaria parasite,
Plasmodium falciparum, which does occur in South Africa, explained UP’s Institute for Sustainable Malaria Control research chair, Professor Lyn-Marie Birkholtz.
The malaria-causing parasite is able to take on multiple forms. Some cause disease, and others allow the parasite to be transmitted back into mosquitos, to continue the deadly life cycle. ....

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