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Understanding antibodies to avoid pandemics

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Photo courtesy of Caltech.
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Last month, the world welcomed the rollout of vaccines that may finally curb the Covid-19 pandemic. Pamela Björkman
, the David Baltimore Professor of Biology and Bioengineering at Caltech, wants to understand how antibodies like the ones elicited by these vaccines target the SARS-CoV-2 virus that causes Covid-19. She hopes this understanding will guide treatment strategies and help design vaccines against future pandemics. She shared her lab’s work during the MIT Department of Biology’s Independent Activities Period (IAP) seminar series, Immunity from Principles to Practice, on Jan. 12.
“Pamela is an amazing scientist, a strong advocate for women in science, and has a stellar history of studying the structural biology of virus-antibody interactions,” says Whitehead Institute for Biomedical Research Member Pulin Li, the Eugene Bell Career Development Pro ....

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Nanoparticle-technology Could Protect from Coronaviruses

Nanoparticle-technology Could Protect from Coronaviruses
by Angela Mohan on
January 13, 2021 at 12:32 PM
Researchers are working on developing vaccines for various related coronaviruses, with the aim of preventing future pandemics in the laboratory of Pamela Björkman especially by the David Baltimore Professor of Biology and Bioengineering.
The SARS-CoV-2 virus that is causing the COVID-19 pandemic is just one of many different viruses in the coronavirus family. Many of these are circulating in populations of animals like bats and have the potential to jump into the human population, just as SARS-CoV-2 did.
Now, led by graduate student Alex Cohen, a Caltech team has designed a protein-based 60-subunit nanoparticle onto which pieces of up to eight different types of coronavirus have been attached. When injected into mice, this vaccine induces the production of antibodies that react to a variety of different coronaviruses including simila ....

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Nanoparticle Vaccine Technology Introduces Immune System to a Variety of Different Coronaviruses

A Caltech team has designed a protein-based 60-subunit nanoparticle onto which pieces of up to eight different types of coronavirus have been attached. When injected into mice, this vaccine induces the production of antibodies that react to a variety of different coronaviruses including similar viruses that were not presented on the nanoparticle. ....

Alex Cohen , University Of Oxford , David Baltimore Professor , அலெக்ஸ் கோஹன் , பல்கலைக்கழகம் ஆஃப் ஆக்ஸ்ஃபர்ட் , டேவிட் பால்டிமோர் ப்ரொஃபெஸர் ,

New technology could protect against different coronavirus variants

New technology could protect against different coronavirus variants
The SARS-CoV-2 virus that is causing the COVID-19 pandemic is just one of many different viruses in the coronavirus family.
Many of these are circulating in populations of animals like bats and have the potential to jump into the human population, just as SARS-CoV-2 did. Researchers in the laboratory of Pamela Björkman, the David Baltimore Professor of Biology and Bioengineering, are working on developing vaccines for a wide range of related coronaviruses, with the aim of preventing future pandemics.
Now, led by graduate student Alex Cohen, a Caltech team has designed a protein-based 60-subunit nanoparticle onto which pieces of up to eight different types of coronavirus have been attached. ....

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Nanoparticle Immunization Technology Could Protect Against Many Strains of Coronaviruses

The SARS-CoV-2 virus that is causing the COVID-19 pandemic is just one of many different viruses in the coronavirus family. Many of these are circulating. ....

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