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IMAGE: Scientists have now discovered that cells sometimes liberate DNA fragments at sites of paired, or double, DSBs.
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Credit: © Franz Klein, Chromosomenbiologie, Universität Wien
Scientists from the lab of Franz Klein from the Department of Chromosome Biology at the Max Perutz Labs, a joint venture of the University of Vienna and the Medical University of Vienna, have now discovered that cells sometimes liberate DNA fragments at sites of paired, or double, DSBs. Whilst this presents an obvious risk of germline mutations as a consequence of erroneous repair or of integration of fragments from elsewhere at break sites, it may also be a source of evolutionary diversity. The study is published as a research article in ....

Franz Klein , Silvia Prieler , Doris Chen , Department Of Chromosome Biology , University Of Vienna , Chromosome Biology , Max Perutz Labs , Medical University , Cell Biology , Medicine Health , ஃப்ரான்ஸ் க்ளீன் , டோரிஸ் சென் , பல்கலைக்கழகம் ஆஃப் வியன்னா , குரோமோசோம் உயிரியல் , மருத்துவ பல்கலைக்கழகம் ,