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Fingerprint ridges carry nerve endings that make us hypersensitive

Leonardo Carneiro de Almeida / Getty
Our fingertips have an extraordinarily high sensitivity to touch – and now it looks like that sensitivity might be largely confined to the ridges of our fingerprints.
“They really help us get very detailed information about what we touch,” says Ewa Jarocka at Umeå University in Sweden.
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Scientists have suspected that our circular, winding fingerprints might have evolved to improve our ability to grip objects by creating better friction, says Jarocka. But she says others have suggested they might contribute to our “very refined sense of touch”.
Because current models can’t explain the high levels of sensitivity people have shown in past scientific studies, Jarocka and her colleagues decided to investigate. ....

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Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease

Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease
Charcot-Marie Tooth disease is the most common hereditary neurological disease in the world. It affects the peripheral nerves and causes progressive paralysis of the legs and hands.
No treatment is currently available to fight this disease, which is due to the overexpression of a specific protein. Scientists from the CNRS, INSERM, the AP-HP and the Paris-Saclay and Paris universities have developed a therapy based on degrading the coding RNA for this protein in mice. Their work is patented and was published on 9 March 2021 in
Communications Biology.
In molecular biology, transcription is when a DNA molecule is copied to make an RNA molecule. This RNA molecule is then translated into a protein, which can perform different functions within the body s cells. When a specific protein called PMP22 is made twice as much as normal, it causes type 1A of genetic Charcot-Marie Tooth disease t ....

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Silver Tiger Metals Inc.: Silver Tiger Intersects 2.95 Meters Grading 1,941.1 g/t AgEq within 9.3 meters of 638.4 g/t AgEq in the Sooy Vein

Silver Tiger Metals Inc.: Silver Tiger Intersects 2.95 Meters Grading 1,941.1 g/t AgEq within 9.3 meters of 638.4 g/t AgEq in the Sooy Vein
Not true width.
Silver Equivalent ( EqAg ) ratios are based on a silver to gold price ratio of 75:1 (Au:Ag). Copper, lead and zinc are converted using $3.66/lb copper, $0.90/lb lead, $1.26/lb zinc at 100% metal recoveries based on a silver price of $26.00/oz.
Drill Hole Location Table
El Tigre Cross Sections 4825N
Plan Map of El Tigre Veins and Drill Holes
El Tigre Resource Estimate
After acquiring El Tigre, Silver Tiger drilled 12,500 meters to define the wide halo of near surface gold mineralization around the mined high-grade veins of the historic El Tigre Mine. This allowed Silver Tiger to deliver a maiden resource estimate for the El Tigre Property to a depth of 150 meters containing indicated resources of 661,000 gold equivalent ounces at 0.77 g/t (21 g/t silver and 0.51 g/t gold) and inferred resources of 3 ....

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Researchers create new nerve cells, spur recovery after spinal cord injury

Using genetic engineering, researchers at UT Southwestern and Indiana University have reprogrammed scar-forming cells in mouse spinal cords to create new nerve cells, spurring recovery after spinal cord injury. ....

Chun Li Zhang , Ww Caruth Jr , Emily Henderson , Indiana University , Ut Southwestern Medical Center , Scholar In Biomedical Research , Cell Stem , Biomedical Research , Study Leader , Molecular Biology , Genetic Engineering , Heart Rate , Spinal Cord Injury , சுன் லி ஜாங் , வ்வ் கருத் ஜூனியர் , எமிலி ஹென்டர்சன் , இந்தியானா பல்கலைக்கழகம் , உட் தென்மேற்கு மருத்துவ மையம் , அறிஞர் இல் உயிர் மருத்துவ ஆராய்ச்சி , செல் தண்டு , உயிர் மருத்துவ ஆராய்ச்சி , படிப்பு தலைவர் , மூலக்கூறு உயிரியல் , ஜெநெடிக் பொறியியல் , இதயம் ரேட் , முதுகெலும்பு தண்டு காயம் ,

Discovery offers a precise route to treat inflammation associated with neuropathic pain

Discovery offers a precise route to treat inflammation associated with neuropathic pain
One of the hallmarks of chronic pain is inflammation, and scientists at the UNC School of Medicine have discovered that anti-inflammatory cells called MRC1
+ macrophages are dysfunctional in an animal model of neuropathic pain. Returning these cells to their normal state could offer a route to treating debilitating pain caused by nerve damage or a malfunctioning nervous system.
The researchers, who published their work in
Neuron, found that stimulating the expression of an anti-inflammatory protein called CD163 reduced signs of neuroinflammation in the spinal cord of mice with neuropathic pain. ....

Jesse Niehaus , Mark Zylka , Emily Henderson , Centers For Disease , School Of Medicine , Neuroscience Center , University Of North Carolina School Medicine , Study Senior Author , North Carolina School , Kenan Distinguished Professor , Cell Biology , Disease Control , Chronic Pain , Animal Model , Anti Inflammatory , Nervous System , Neuropathic Pain , ஜெஸ்ஸி னீேோச் , எமிலி ஹென்டர்சன் , மையங்கள் க்கு நோய் , பள்ளி ஆஃப் மருந்து , நரம்பியல் மையம் , பல்கலைக்கழகம் ஆஃப் வடக்கு கரோலினா பள்ளி மருந்து , படிப்பு மூத்தவர் நூலாசிரியர் , வடக்கு கரோலினா பள்ளி , கெணான் புகழ்பெற்ற ப்ரொஃபெஸர் ,