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A tale of transgenic mice: Heart failure medication might prevent, and reverse Alzheimer’s Disease
How do we treat Alzheimer’s Disease (AD)? Almost every professional that has worked closely with dementia patients knows that AD is progressive and fatal. But what if it isn’t? What if there was a drug that could prevent or even treat it? 
As of today, AD is a progressive neurodegenerative disorder, the most common type of dementia that in advanced stages, causes severe memory and learning impairments as well as loss of motor function. One of the hallmarks of a brain affected by AD is the presence and accumulation of a sticky protein called beta-amyloid (Aβ), or Aβ plaques between nerve cells. This accumulation and deposition is thought to disrupt cell-to-cell communication and ultimately result in neuronal cell death and decreased brain volume. It is believed to be the primary driving force of AD pathogenesis. This idea, which is referred to as the “amyloid hypoth ....

Patricia Sharleen , Wayne Chen , Jinjing Yao , Sr Wayne Chen , Zaved Khan Research Gate , University Of Calgary , Libin Cardiovascular Institute University Of Calgary , Libin Cardiovascular , Cell Reports , Time Prevents Alzheimer , Disease Related Neuronal Hyperactivity , Memory Loss , பாட்ரிசியா ஷார்லீன் , வேன் சென் , ர்ரைவ் வேன் சென் , ஜாவெத் காந் ஆராய்ச்சி வாயில் , பல்கலைக்கழகம் ஆஃப் கல்கரி , செல் அறிக்கைகள் , நேரம் ப்ரிவெஂட்ஸ் முதுமறதி , நினைவு இழப்பு ,