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A new polarized fluorescent probe for revealing architectural dynamics of living cells


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VIDEO: Time-lapse movies of the polarized fluorescence imaging during the first cleavage of a starfish embryo expressing POLArIS that specifically binds to F-actin in a rotationally constrained manner (the same egg.
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Credit: Department of Neuroanatomy and Cellular Neurobiology,TMDU
Researchers from Tokyo Medical and Dental University (TMDU), collaborating with scientists from the Marine Biological Laboratory (MBL) and RIKEN, develop a novel technique for live-cell fluorescent imaging which leads them to discover a new actin structure in starfish early embryos.
Tokyo, Japan - Monitoring alignments of the building blocks of cells is important to understand how the cells are built. By collaborating with imaging scientists at the MBL, researchers from Japan have developed a new probe which they call POLArIS, allowing real-time imaging of molecular orientations in live cells. ....

Keisuke Sato , Ayana Sugizaki , Sumio Terada , Tomomi Tani , Marine Biological Laboratory , National Institute Of Advanced Industrial Science , Tokyo Medical , Dental University , Green Fluorescent Protein , Senior Researcher , National Institute , Advanced Industrial Science , Associate Scientist , Biomechanics Biophysics , Cell Biology , Developmental Reproductive Biology , Molecular Biology , கேசுக்கே ஸாடோ , கடல் உயிரியல் ஆய்வகம் , டோக்கியோ மருத்துவ , டெஂடல் பல்கலைக்கழகம் , பச்சை ஒளிரும் ப்ரோடீந் , மூத்தவர் ஆராய்ச்சியாளர் , தேசிய நிறுவனம் , இணை விஞ்ஞானி ,