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PATH and University of Queensland create custom proteins for malaria diagnostics

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A global health organisation and state-of-the-art laboratory at The University of Queensland are collaborating to support the development and evaluation of point-of-care diagnostics for malaria with new custom-made proteins.
PATH and UQ’s Protein Expression Facility will supply researchers with malaria proteins to improve point-of-care diagnostic tools and help reduce the burden of malaria, which continues to affect more than 200 million people and cause more than 400,000 deaths each year.
Director of UQ’s Protein Expression Facility Professor Linda Lua said the partnership would help malaria researchers develop new diagnostic tools.
“New tools to enable the development of highly sensitive diagnostics are urgently needed to reduce disease and death attributable to malaria,” Professor Lua said. ....

Gonzalo Domingo , Linda Lua , Diagnostics Program , University Of Queensland , Melinda Gates Foundation , Protein Expression Facility , Expression Facility , Professor Linda Lua , Scientific Director , Melinda Gates , கோன்சலோ டொமிஂகொ , லிண்டா லூ , பரிசோதனை ப்ரோக்ர்யாம் , பல்கலைக்கழகம் ஆஃப் குயின்ஸ்லாந்து , மெலிண்டா வாயில்கள் அடித்தளம் , ப்ரோடீந் வெளிப்பாடு வசதி , வெளிப்பாடு வசதி , ப்ரொஃபெஸர் லிண்டா லூ , அறிவியல் இயக்குனர் , மெலிண்டா வாயில்கள் ,

MRI frequently underestimates tumor size in prostate cancer

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A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center has found that magnetic resonance imaging, or MRI, frequently underestimates the size of prostate tumors, potentially leading to undertreatment.
The study authors found that such underestimation occurs most often when the MRI-measured tumor size is small and the PI-RADS score, which is used to classify lesions in prostate MRI analysis, is low.
For prostate tumor treatments to be successful, both the MRI size measurement and PI-RADS score must be accurate because they allow physicians to determine precisely where tumors end and where the normal, healthy tissue surrounding them begins. ....

Amirhossein Bajgiran , David Johnson , Steven Raman , Sohrab Mirak , Robert Reiter , Daniela Markovic , Alexa Hughes , Taylor Sadun , Ely Felker , Aydin Pooli , Anthony Sisk , Department Of Pathology , Department Of Radiological Sciences , David Geffen School Of Medicine , Diagnostics Program , Laboratory Medicine , Jonsson Comprehensive Cancer Center , Comprehensive Cancer Center , David Geffen School , Joseph Shirk , Integrated Diagnostics Program , Radiological Sciences , டேவிட் ஜான்சன் , ஸ்டீவன் ராமன் , சோஹ்ராப் அதிசயம் , ராபர்ட் ரைடர் ,