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Study provides new insight on how HER2-low tumors may evolve in breast cancer patients


Study provides new insight on how HER2-low tumors may evolve in breast cancer patients
The finding that breast tumors can evolve to express low HER2 potentially widens the number of patients who can benefit from new investigational agents, typically novel antibody-drug conjugate therapies, that are currently in clinical trials for HER2-low tumors.
The first study of its kind exploring how breast cancers change from the primary to the recurrent tumor has revealed that nearly 30% of breast cancer patients convert from, or to, human epidermal growth factor receptor (HER)2-low status. Specifically, the study found that 14% of triple-negative breast cancers with HER2-negative expression (also referred to as HER2-0) in the primary tumor converted to HER2-low expression in the recurrent tumor possibly offering an option to such hard-to-treat tumors. ....

Comunidad Autonoma De Cataluna , Aleix Prat , Emily Henderson , School Of Oncology , University Of Padua , Cancer Virtual Congress , Federica Miglietta , Professor Aleix Prat , Head Medical Oncology , Hospital Clinic , காமுனிடட தன்னாட்சி டி கடலுள் , எமிலி ஹென்டர்சன் , பள்ளி ஆஃப் புற்றுநோயியல் , பல்கலைக்கழகம் ஆஃப் ப்யாட்யூவ , தலை மருத்துவ புற்றுநோயியல் , மருத்துவமனை சிகிச்சையகம் ,

Switch of breast tumors to HER2-low might provide greater therapeutic options


Switch of breast tumors to HER2-low might provide greater therapeutic options
ANI |
Updated: May 09, 2021 18:56 IST
Lugano [Switzerland], May 9 (ANI): The finding that breast tumours can evolve to express low HER2 potentially widens the number of patients who can benefit from new investigational agents, typically novel antibody-drug conjugate therapies, that are currently in clinical trials for HER2-low tumours.
The first study of its kind exploring how breast cancers change from the primary to the recurrent tumour has revealed that nearly 30% of breast cancer patients convert from, or to, human epidermal growth factor receptor (HER)2-low status. The study was published in the journal Annals of Oncology. ....

Italy General , Comunidad Autonoma De Cataluna , Aleix Prat , School Of Oncology , University Of Padua , Cancer Virtual Congress , Professor Aleix Prat , Head Medical Oncology , Hospital Clinic , இத்தாலி ஜநரல் , காமுனிடட தன்னாட்சி டி கடலுள் , பள்ளி ஆஃப் புற்றுநோயியல் , பல்கலைக்கழகம் ஆஃப் ப்யாட்யூவ , தலை மருத்துவ புற்றுநோயியல் , மருத்துவமனை சிகிச்சையகம் ,

Switch of breast tumors to HER2-low in recurrence may provide greater therapeutic options


European Society for Medical Oncology
The finding that breast tumours can evolve to express low HER2 potentially widens the number of patients who can benefit from new investigational agents, typically novel antibody-drug conjugate therapies, that are currently in clinical trials for HER2-low tumours.
The first study of its kind exploring how breast cancers change from the primary to the recurrent tumour has revealed that nearly 30% of breast cancer patients convert from, or to, human epidermal growth factor receptor (HER)2-low status. Specifically, the study found that 14% of triple-negative breast cancers with HER2-negative expression (also referred to as HER2-0) in the primary tumour converted to HER2-low expression in the recurrent tumour possibly offering an option to such hard-to-treat tumours. ....

Comunidad Autonoma De Cataluna , Aleix Prat , School Of Oncology , University Of Padua , Cancer Virtual Congress , Professor Aleix Prat , Head Medical Oncology , Hospital Clinic , காமுனிடட தன்னாட்சி டி கடலுள் , பள்ளி ஆஃப் புற்றுநோயியல் , பல்கலைக்கழகம் ஆஃப் ப்யாட்யூவ , தலை மருத்துவ புற்றுநோயியல் , மருத்துவமனை சிகிச்சையகம் ,

Moodle.org: Moodle jobs


Type: Contract
Location: Based on site (the Christie trust) with opportunity for home working (can be discussed at interview)
The Christie School of Oncology provides specialist education programmes at the largest single-site cancer centre in Europe and one of the top-rated cancer hospitals worldwide. 
A rare opportunity for a talented and creative learning development specialist has arisen within our Digital Learning team, to support the increased demand for the team’s high quality services.
You will play an important role within our expanding professional team, leading end-to-end production of multiple projects involving utilisation of specialist learning development software. 
You will be a highly motivated individual with the ability to hit the ground running. You will have expertise in all aspects of learning development, including virtual learning environment managements, educational development and graphic design. ....

School Of Oncology , Christie School Of Oncology , Christie School , Digital Learning , Virtual Learning Environment , Senior Learning Technologist , Digital Learning Manager , Moodle Org Jobs , பள்ளி ஆஃப் புற்றுநோயியல் , கிறிஸ்டி பள்ளி ஆஃப் புற்றுநோயியல் , கிறிஸ்டி பள்ளி , டிஜிட்டல் கற்றல் , மெய்நிகர் கற்றல் சூழல் , மூத்தவர் கற்றல் தொழில்நுட்பவியலாளர் , டிஜிட்டல் கற்றல் மேலாளர் ,