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Parkinson's disease: blood changes may occur years before diagnosis


Although Parkinson’s disease affects around 1%-2% of people over the age of 65, there is currently no cure. And by the time it is diagnosed – typically by identifying problems with movement, such as slower movements and tremors – the changes in the brain it causes are irreversible. So being able to identify Parkinson’s earlier will be important in finding ways to prevent and cure the disease.
In our latest study, my colleagues and I have identified changes in blood that occur years before a Parkinson’s diagnosis. This could lead to earlier diagnosis of the disease.
The causes of Parkinson’s aren’t completely understood, but clear links have been established with genetic and environmental risk factors – such as exposure to certain pesticides and solvents. However, we do know that Parkinson’s disease causes the death of certain nerve cells in the brain, due to a combination of abnormal protein accumulation in cells, problems with mitochrondia (the “power ....

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