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Combination Therapy & Radiation Holds Promise in Glioblastoma by Angela Mohan on February 10, 2021 at 2:14 PM Anti-psychotic drug and a statin combination along with radiation improves the overall survival in mice with glioblastoma, as per the study done on mice by the team of researchers at the UCLA Jonsson Comprehensive Cancer Center. Glioblastoma is one of the deadliest and most difficult-to-treat brain tumors. Researchers found the triple combination extended the median survival 4-fold compared to radiation alone. Radiation therapy is part of the standard-of-care treatment regimen for glioblastoma, often helping prolong the survival of patients. However, survival times have not improved significantly over the past two decades and attempts to improve the efficacy of radiotherapy through the use of pharmaceuticals have been hampered by the normal tissue toxicity of the drugs and the inability to penetrate the blood-brain barrier. ....