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'Invisible' Deep-Sea Bacteria Cause Researchers to Rethink Human Immune Systems

‘Invisible’ Deep-Sea Bacteria Cause Researchers to Rethink Human Immune Systems
Image: Schmidt Ocean Institute
Researchers have found microbes in the deep sea that are completely invisible to the human immune system, a somewhat unnerving discovery that suggests our bodies’ seemingly universal ability to recognize bacteria isn’t so all-inclusive.
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The interdisciplinary team’s research was published last week in the journal Science Immunology. Their fundamental conclusion is that the way our mammalian immune systems sniff out trouble the rules and patterns we follow to protect ourselves may be defined locally rather than globally, a finding that goes against a long-held belief in immunology. These marine microbes have never been in contact with mammalian life before, not even marine mammals, according to the researchers. ....

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Deep Ocean Reveals Surprising Discovery about Human Immunity | The Brink

Scientists from Boston University, Harvard Medical School and others find new microbes in the deep sea that cannot be detected by human immune cells. ....

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Deep Ocean Reveals Surprising Discovery about Immunity

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Deep Ocean Reveals Surprising Discovery about Immunity
In the largest and deepest marine protected area in the world, a team of ocean experts peered over 3,000 meters below the surface to find new types of microbial organisms that people would have never encountered before. These microbes-types of bacteria-could now open up doors to new ways of understanding how the immune system responds to completely foreign invaders.
A collaborative study between the Rotjan Marine Ecology Lab at Boston University, the Kagan Lab at the Harvard Medical School, Boston Children’s Hospital, the government of Kiribati, and others has found that there are some bacteria so foreign to humans that our immune cells can’t register that they exist, overriding the long-held belief of universal immunity, or that our cells can recognize any bacteria they interact with. Rather, the study found, some bacteria are solely defined by their local habitat or surroundings. Their findings were ....

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