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Rates of Erythrocytosis in Trans Males Consistent with Cis Males

Rates of Erythrocytosis in Trans Males Consistent with Cis Males
New research found that the greatest increases in hematocrit occurred during the first year of treatment but levels continue to increase over time until around the 20 year mark
With Milou Madsen MD and Alex Pastuszak MD
In the decade between 2001 and 2011, the number of prescriptions for testosterone for men over 40 tripled. It quadrupled for those 18-45. These sharp increases in men starting hormone therapy after reporting symptoms of hypogonadism has led some to speculate on the side effects of testosterone therapy, including erythrocytosis. This increase in the red blood cell population can result in symptoms that can be health or life-threatening, including obstructive sleep apnea, kidney stones, stroke, deep vein thrombosis or heart attack. ....

Noord Holland , Milou Cecilia Madsenm , University Of Amsterdam Medical Center , University Of Utah , With Milou Madsen , Alex Pastuszak , Large Cohort , Trans Men Using Testosterone , Long Term Follow , Milous Madsen , Amsterdam Medical Center , Gender Dysphoria , Alexander Pastuszak , நூற்த் ஹாலண்ட் , பல்கலைக்கழகம் ஆஃப் ஆம்ஸ்டர்டாம் மருத்துவ மையம் , பல்கலைக்கழகம் ஆஃப் உட்டா , பெரியது கூட்டுறவு , டிரான்ஸ் ஆண்கள் பயன்படுத்தி டெஸ்டோஸ்டிரோன் , நீண்டது கால பின்தொடரவும் , ஆம்ஸ்டர்டாம் மருத்துவ மையம் ,

PPIs can independently cause QTc prolongation, study finds

PPIs can independently cause QTc prolongation, study finds
Updated On 7 July 2021 5:37 AM GMT
Italy: A recent study has provided strong evidence that proton pump inhibitors (PPIs) in themselves can promote QTc prolongation through the inhibition of hERG function.
Considering the above, there is a need for careful evaluation of the benefit-risk ratio whenever PPIs are given to patients with other QT-prolonging risk factors, even in the absence of hypomagnesemia, the authors wrote in the journal
Circulation: Arrhythmia and Electrophysiology.
PPIs, medications that work by reducing the production of stomach acid, are used widely worldwide, often without a compelling indication. Previous studies have shown PPI use to be associated with increased mortality partly due to a higher risk of QTc-related malignant arrhythmias. ....

Pietro Enea Lazzerini , University Of Siena , Pump Inhibitors Directly Block , Independently Increase , Large Cohort , பல்கலைக்கழகம் ஆஃப் ஸியீந , பெரியது கூட்டுறவு ,

Analiza przebiegu klinicznego zakażenia SARS-CoV-2 u pacjentów zakażonych HIV - Przegląd badań - AIDS

Analiza przebiegu klinicznego zakażenia SARS-CoV-2 u pacjentów zakażonych HIV
21.04.2021
Na podstawie: Clinical Outcomes and Inflammatory Markers by HIV Serostatus and Viral Suppression in a Large Cohort of Patients Hospitalized With COVID-19
Viraj V. Patel i wsp.
J. Acquir. Immune Defic. Syndr. 2021; 86: 224–230 ....

Clinical Outcomes , Inflammatory Markers , Viral Suppression , Large Cohort , Patients Hospitalized With , மருத்துவ ஔட்கம்ஸ் , அழற்சி குறிப்பான்கள் , வைரஸ் அடக்குமுறை , பெரியது கூட்டுறவு ,