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Regulatory mechanisms of lncRNAs in cancer glycolysis


163 are also involved in resistance to cisplatin, temozolomide and 5-fluorouracil via altering glycolysis in gastric cancer, glioblastoma and CRC, respectively. Interestingly, Fu et al reported that lncRNA plasmacytoma variant translocation 1 (PVT1) maintains Myc expression in Sjögren’s syndrome. This expression regulates proliferation and immune effects of CD4
+ T cells by controlling glycolytic metabolism.
164 Investigating the role of the PVT1-T cell glycolysis axis in tumor models may provide a novel insight for improving T cell-based immunotherapy.
The important role of lncRNAs-mediated glucose metabolic reprogramming in cancer adjuvant therapy, as discussed above, makes them promising targets for treating cancers. Several studies have revealed that siRNA, antisense oligonucleotides (ASOs) and clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) may be promising methods of targeting lncRNAs. ....

Gong Long , Hali Long , Cao Long , Chen Long , Asong Long , South Korea , Wum Lnc , Biochim Biophys Acta , Sonveauxp Monocarboxylate , Al Hasawi , El Amrani , Chemother Pharmacol , Chengdu University Of Traditional Chinese Medicine , Foundation Of Science , Technology Department Of Sichuan Province , Ethics Approval , Technology Department , Sichuan Province , Chengdu University , Traditional Chinese Medicine , Postdoctoral Science Foundation , Drug Resist , Mol Life , Exp Med , Cell Dev , Nat Rev ,

Researchers reveal relationship between magnetic field and supercapacitors


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IMAGE: Figure 1. The drawing of test apparatus and capacitance changes at different scan rates in different electrolytes under magnetic field.
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Credit: LICP
Since energy storage devices are often used in a magnetic field environment, scientists have often explored how an external magnetic field affects the charge storage of nonmagnetic aqueous carbon-based supercapacitor systems.
Recently, an experiment designed by Prof. YAN Xingbin s group from the Lanzhou Institute of Chemical Physics (LICP) of the Chinese Academy of Sciences has revealed that applying an external magnetic field can induce capacitance change in aqueous acidic and alkaline electrolytes, but not in neutral electrolytes. The experiment also shows that the force field can explain the origin of the magnetic field effect. ....

Postdoctoral Science Foundation Of China , Technology Bureau Of China , National Natural Science Foundation Of China , Lanzhou Institute Of Chemical Physics , Chinese Academy Of Sciences , Lanzhou Institute , Chemical Physics , Chinese Academy , Cell Reports Physical Science , National Natural Science Foundation , Postdoctoral Science Foundation , Zhaoqing Municipal Science , Technology Bureau , Chemistry Physics Materials Sciences , போஸ்ட்‌டாக்டொரல் அறிவியல் அடித்தளம் ஆஃப் சீனா , தொழில்நுட்பம் பணியகம் ஆஃப் சீனா , தேசிய இயற்கை அறிவியல் அடித்தளம் ஆஃப் சீனா , லான்ஷோ நிறுவனம் ஆஃப் இரசாயன இயற்பியல் , சீன கலைக்கழகம் ஆஃப் அறிவியல் , லான்ஷோ நிறுவனம் , இரசாயன இயற்பியல் , சீன கலைக்கழகம் , செல் அறிக்கைகள் உடல் அறிவியல் , தேசிய இயற்கை அறிவியல் அடித்தளம் , போஸ்ட்‌டாக்டொரல் அறிவியல் அடித்தளம் , தொழில்நுட்பம் பணியகம் ,