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IQWiG's new threshold proven feasible in practice for early benefit assessments of drugs

IQWiG s new threshold proven feasible in practice for early benefit assessments of drugs
Current examples prove the feasibility of the 15 percent threshold newly defined by IQWiG for the acceptance of responder analyses in early benefit assessments of drugs.
In order to show the clinical relevance of a difference between two treatment alternatives, in recent years, the manufacturer dossiers submitted in early benefit assessments of new drugs have increasingly contained responder analyses for patient-relevant outcomes.
In such analyses, it is investigated whether the proportion of patients experiencing a noticeable change in the respective outcome differs between the two treatment groups in a study. ....

Katrin Nink , Emily Henderson , Iqwig Drug Assessment Department , General Methods , Drug Assessment Department , Drug Assessment , Breast Cancer , Cystic Fibrosis , Psoriatic Arthritis , எமிலி ஹென்டர்சன் , ஜநரல் முறைகள் , மருந்து மதிப்பீடு துறை , மருந்து மதிப்பீடு , மார்பக புற்றுநோய் , சிஸ்டிக் ஃபைப்ரோஸிஸ் , சொரியாடிக் கீல்வாதம் ,

Nusinersen in SMA: indication of major added benefit in children with early-onset disease

Nusinersen in SMA: indication of major added benefit in children with early-onset disease
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Beate Wieseler , Iqwig Drug Assessment Department , Efficiency In Health Care Iqwi , German Institute For Quality , German Institute , Health Care , Drug Assessment Department , Federal Joint Committee , ஜெர்மன் நிறுவனம் க்கு தரம் , ஜெர்மன் நிறுவனம் , ஆரோக்கியம் பராமரிப்பு , மருந்து மதிப்பீடு துறை , கூட்டாட்சியின் கூட்டு குழு ,

Clinical relevance of patient-reported outcomes: new threshold proven feasible in practice

Clinical relevance of patient-reported outcomes: new threshold proven feasible in practice
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Katrin Nink , Iqwig Drug Assessment Department , General Methods , Drug Assessment Department , ஜநரல் முறைகள் , மருந்து மதிப்பீடு துறை ,

From publication bias to lost in information

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The availability of clinical trial records has increased markedly in recent years. For instance, several documents from numerous sources are often available for a single clinical trial - sometimes with overlapping, but often incomplete information.
Identifying and processing this information involves a great deal of resources and challenges. Using an example of information retrieval for a health technology assessment report, this is shown in the current issue of
BMJ Evidence-Based Medicine by two researchers from the German Institute for Quality and Efficiency in Health Care (IQWiG): Beate Wieseler from the Drug Assessment Department and Natalie McGauran from the Communications Unit. ....

Beate Wieseler , Natalie Mcgauran , Communications Unit , Drug Assessment Department , Efficiency In Health Care Iqwi , German Institute For Quality , Based Medicine , German Institute , Health Care , தகவல்தொடர்புகள் அலகு , மருந்து மதிப்பீடு துறை , ஜெர்மன் நிறுவனம் க்கு தரம் , அடிப்படையிலானது மருந்து , ஜெர்மன் நிறுவனம் , ஆரோக்கியம் பராமரிப்பு ,