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Karolinska Development AB (publ): Karolinska Development's portfolio company Modus Therapeutics prepares clinical development program of sevuparin in sepsis/septic shock


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STOCKHOLM, SWEDEN - March 10, 2021. Karolinska Development AB (Nasdaq Stockholm: KDEV) announces today that its portfolio company Modus Therapeutics is preparing a clinical development program of its drug candidate sevuparin in patients suffering from sepsis/septic shock, and possibly also other severe inflammatory conditions arising in conjunction with major trauma, surgery, autoimmunity and viral infections. Modus Therapeutics expects to start the first clinical trial in this new indication around the end of 2021. Sevuparin has already demonstrated a favorable safety profile in clinical trials for other indications.
Patients suffering from sepsis are at risk of developing septic shock and multi-organ failure. Septic shock is a leading cause of death in intensive care units, with mortality rates typically exceeding 30 percent. There is currently no specific pharmaceutical treatment available for the treatment of sepsis. As a result, it is one of the costliest conditio ....

Karolinska Institutet , Johan Dighed , Viktor Drvota , Karolinska Development Ab Nasdaq Stockholm , Karolinska Development , Nasdaq Stockholm , Modus Therapeutics , Modus Therapeutic , General Counsel , நாஸ்டாக் ஸ்டாக்‌ஹோல்ம் , மோடஸ் சிகிச்சை , ஜநரல் ஆலோசனை ,