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Top News In வால்டர் மற்றும் எலிசா மண்டபம் நிறுவனம் Today - Breaking & Trending Today

Reason for Neonatal Strokes Identified!

Important cause of neonatal strokes occurring in the womb or just after birth has been discovered by scientists, which further paves the way for new treatments.

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Walter And Eliza Hall Institute , வால்டர் மற்றும் எலிசா மண்டபம் நிறுவனம் , Eonatal Strokes , Stroke Causes , Troke Treatments ,

New cellular atlas maps out healthy and cancerous breast tissue


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New cellular atlas maps out healthy and cancerous breast tissue
WEHI researchers have documented the diversity of cells in the human breast, explaining the relationship between healthy breast cells and breast cancer cells.
The diversity of cells in the human breast has been
documented in a new ‘RNA atlas’.
The research, which relied on expertise spanning from breast cancer biology through to bioinformatics, measured gene expression in single cells taken from healthy women and cancerous breast tissue, including tissue carrying a faulty BRCA1 gene. This enabled the researchers to create an ‘RNA atlas’ that details the different cells found in these tissues. ....

Tony Papenfuss , Jane Visvader , Geoff Lindeman , Gordon Smyth , Yunshun Chen , Rachel Joyce , Bhupinder Pal , Stephen Wilcox , Jocelyn Penington , Vanessa Bryant , Nina Tubau Ribera , Bianca Capaldo , National Health , Qualtrough Cancer Research Fund , Michael Heine Family Foundation , Ian Potter Foundation , Australian Cancer Research Foundation , National Breast Cancer Foundation , Research Council , Olivia Newton John Cancer Research Institute , Professor Jane Visvader , Professor Gordon Smyth , Professor Geoff , Professor Visvader , Professor Smyth , Victorian Cancer Biobank ,

Natural immunity to malaria provides clues to potential therapies


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Natural immunity to malaria provides clues to potential therapies
WEHI researchers have identified how natural human antibodies can block malaria parasites from entering red blood cells, potentially indicating how new protective therapies could be developed against this globally significant disease.
Dr Melanie Dietrich, Li Jin Chan and Associate Professor
Wai-Hong Tham
The research provides greater insight into how antibodies block the entry of Plasmodium vivax malaria parasites into young red blood cells called reticulocytes. It builds on an earlier discovery that the P. vivax latches onto the transferrin receptor 1 (TfR1) to enter cells.
The research, led by Associate Professor Wai-Hong Tham and PhD student Li-Jin Chan from WEHI, alongside Professor Christopher King from Case Western University, US, was published in Nature Communications. ....

Papua New Guinea , Li Jin Chan , Christopher King , Melanie Dietrich , Sebastien Menant , Camila Fran , Ivo Mueller , Nature Communications , National Health , Case Western University , European Research Council , Research Council , Associate Professor Wai Hong Tham , Professor Christopher King , Associate Professor Tham , Professor Tham , Medical Research Council , Jin Chan , Walter And Eliza Hall Institute , European Research Council , Nature Communications , Western University , Papua New Guinea , Research Council , Medical Research , பப்புவா புதியது கினியா ,

Nanobodies inhibit SARS-CoV-2 infection


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Nanobodies inhibit SARS-CoV-2 infection
Australian researchers have identified neutralising nanobodies that block the SARS-CoV-2 virus from entering cells in preclinical models.
The discovery paves the way for further investigations into nanobody-based treatments for COVID-19.
Visualisation of SARS-CoV-2 virus with nanobodies (purple)
attaching to the virus ‘spike’ protein.
Image: Dr Drew Berry in collaboration with
Associate Professor Wai-Hong Tham
Published in PNAS, the research is part of a consortium-led effort, bringing together the expertise of Australian academic leaders in infectious diseases and antibody therapeutics at WEHI, the Doherty Institute and the Kirby Institute.
At a glance
Researchers have identified nanobodies that effectively blocked the SARS-CoV-2 virus from entering cells in pre-clinical models of COVID-19 infection. ....

Marcel Doerflinger , Alisa Glukhova , Matthew Oneill , Melanieh Dietrich , Amy Adair , Phillip Pymm , Hariprasad Venugopal , Michael Dengler , Marc Pellegrini , James Cooney , Cody Allison , Li Jin Chan , Doherty Institute , Kirby Institute , Research Future Fund , Monash Ramaciotti Centre For Cryo , Hengyi Group , Professor Wai Hong Tham , Associate Professor Wai Hong Tham , Professor Tham , Monash Ramaciotti Centre , Cryo Electron Microscopy , Senior Microscopist , Medical Research Future Fund , Matthewo Neill , Damien Drew ,