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Unbalanced cell division offers a new target for treating baldness

Unbalanced cell division offers a new target for treating baldness
newatlas.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from newatlas.com Daily Mail and Mail on Sunday newspapers.

Emi Nishimura , Hiroyuki Matsumura , University Of Tokyo , Tokyo Medical , Dental University , ஹீரோயுக்கி மாட்சுமுர , பல்கலைக்கழகம் ஆஃப் டோக்கியோ , டோக்கியோ மருத்துவ , டெஂடல் பல்கலைக்கழகம் ,

Study reveals new mechanism by which hair follicles lose their regenerative capabilities


Study reveals new mechanism by which hair follicles lose their regenerative capabilities
Hair grows from stem cells residing in hair follicles. During aging, the capability of hair follicles to grow hair is successively lost, leading to hair thinning and ultimately hair loss. In a new study, researchers from Tokyo Medical and Dental University (TMDU) and the University of Tokyo identified a novel mechanism by which hair follicles lose their regenerative capabilities.
Hair follicles are mini-organs from which new hair constantly grows. The basis for new hair growth is the proper function of hair follicle stem cells (HFSCs). HFSCs undergo cyclic symmetric and asymmetric cell divisions (SCDs and ACDs). ....

Emi Nishimura , Hiroyuki Matsumura , Emily Henderson , University Of Tokyo , Tokyo Medical , Dental University , Study First Author , Cell Division , Hair Loss , Stem Cells , ஹீரோயுக்கி மாட்சுமுர , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் டோக்கியோ , டோக்கியோ மருத்துவ , டெஂடல் பல்கலைக்கழகம் , படிப்பு முதல் நூலாசிரியர் , செல் பிரிவு , முடி இழப்பு , தண்டு செல்கள் ,

The bald truth - altered cell divisions cause hair thinning

Researchers from TMDU identified a novel mechanism underlying hair thinning and loss during aging. By studying cell division of hair follicle stem cells in young and aged mice, the researchers found that young mice properly balance typical symmetric and asymmetric cell divisions to regenerate hair follicles. However, during aging, an atypical type of asymmetric cell division emerges, leading to hair loss. This study could help develop new approaches to regulate organ aging and aging-associated diseases. ....

Emi Nishimura , Hiroyuki Matsumura , University Of Tokyo , Tokyo Medical , Dental University , Nature Aging , Cell Biology , Molecular Biology , ஹீரோயுக்கி மாட்சுமுர , பல்கலைக்கழகம் ஆஃப் டோக்கியோ , டோக்கியோ மருத்துவ , டெஂடல் பல்கலைக்கழகம் , உயிர் வேதியியல் , செல் உயிரியல் , மூலக்கூறு உயிரியல் ,