Detailed description is Welcome to UBC iGEM's page! Here we'll update you on our progress on bettering the world through synthetic biology for the international iGEM competition. UBC's 2017 iGEM:. The 2017 team engineered Agrobacterium tumefaciens to remove the virulence regions of tumor inducing (Ti) plasmids in the environment, providing the agriculture industry with tools to fight plant pathogens. We equipped our species, aGROW, to express CRISPR/Cas9 and RNA guides targeting the Ti plasmid in the presence of plant wounds. We investigated the conjugative abilities and implemented a plasmid maintenance system to make our solution practical. We built a model to inform CRISPR guide design in modular systems.. More information about our experiments can be seen on our wiki: http://2017.igem.org/Team:British_Columbia. . UBC's 2016 iGEM:. The 2016 team engineered a surface protein expressed on Caulobacter crescentus to degrade raw wood waste into simple sugars for the purpose of feeding the central metabolism of Caulobacter itself, and a co-culture of Escherichia coli. By including the genetic coding for cellulase enzymes in the genetic code for the Rsa-A surface protein, these cellulase enzymes were expressed on the bacteria membrane and could degrade surrounding cellulose into glucose monomers. More information, as well as experimental results and a proof of concept can be seen on the wiki page: http://2016.igem.org/Team:British_Columbia. . UBC’s 2015 iGEM:. The 2015 team created a strain of engineered honeybee intestinal bacterium capable of degrading the neonicotinoid (a widely-used class of pesticides) imidacloprid, alongside an antifungal agent to eliminate Nosema apis (an endoparasite that grows in the midgut of the honeybee following infection). In doing so, they were able to render inoculated honeybees resistant to both Nosema and to common field doses of imidacloprid, allowing its sustained use while reducing the risk of Colony Collapse Disorder. More information, as well as experimental results and a proof of concept can be seen on the wiki page: http://2015.igem.org/Team:British_Columbia
Established in the recent years UBC iGEM in vancouver, british-columbia in canada.
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