"If someone had told me 15 years ago, that I would play 69 Test matches for South Africa and captained the side, I wouldn't have believed them. I stand in a place of utmost gratitude for a Test career full of blessings bestowed on me," he added.
"The next two years are ICC T20 World Cup years. Because of this, my focus is shifting to this format and I want to play as much of it as possible around the world so that I can be the best player I can possibly be," Du Plessis wrote.
He represented South Africa in 69 Tests and scored 4163 runs at an average of 40.02. He scored 10 centuries and registered his highest score of 199 in 2020.