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A year ago, ASCO released a clinical practice guideline on systemic therapy for patients with stage IV non-small cell lung cancer (NSCLC) without driver alterations. Part two has now been released, and it focuses on patients with stage IV NSCLC with driver alterations.
The guideline "is a result of potentially practice-changing evidence published since the last update [in 2017]," noted Gregory Masters, MD, of the ChristianaCare Helen F. Graham Cancer Center and Research Institute in Newark, Delaware, and colleagues.
The updated guideline offers 41 recommendations, including the following:
Patients should be offered targeted therapies against